Pre-analytical, analytical, and post-analytical considerations while processing samples of COVID-19 patients: Perspective from a clinical chemistry laboratory in India

Hemoglobin A1c: Clinical applications and analytical considerations

Diabetes Mellitus (DM) is the most common disorder of carbohydrate metabolism. Hyperglycemia is the common feature of DM. Hyperglycemia causes cardiovascular, renal, ocular, and peripheral nerve disorders in patients with diabetes. Glycemic regulation plays an essential role in controlling these complications. Thus, evaluation of the glycemic control status is crucial in the management of DM. H...

[Vitamin D measurement: pre-analytical and analytical considerations].

The constantly increasing requests for the measurement of serum 25-hydroxyvitamin D over the last years has led reagent manufacturers to market different automated and semi-automated methods, that being unfortunately not fully harmonized, yield different results. Liquid chromatography coupled to tandem mass spectrometry has more recently been introduced. This approach allows the distinction bet...

Signal Processing in Analytical Chemistry

A study of pre-analytical variables in clinical biochemistry laboratory.

OBJECTIVES Pre-analytical error decisively influences the total error and consequently the diagnostic accuracy. The following were the objectives for the study: 1. To detect the percent of pre-analytical errors in clinical biochemistry laboratory. 2. To categorize these pre-analytical errors. 3. To formulate corrective measures to be taken to avoid such errors. DESIGN AND METHODS Study period...

Pre-analytical, analytical and postanalytical considerations in glucose point-of-care testing.

Previous medico-legal autopsy diagnoses after sportrelated deaths in our personal experience in Durban included cardiomyopathy, coronary artery disease, Marfan’s syndrome and ruptured cerebral berry aneurysms. It is regrettable that autopsies were not performed in the above cases. Whether they should have been considered natural or unnatural may be debatable, but postmortem examinations could h...